To create a new project, use the "File" menu and click the "New project" button. This will open the new project wizard dialog. The various parts of this dialog are:

  1. Project title: specify the title of the new project
  2. Project language: specify the main language of the project
  3. Optionally specify an initial table of contents: use the TAB key to create the hierarchy
  4. Import the table of contents from an existing HelpNDoc, CHM or HHP project
  5. Quickly create a new empty project without any items in the table of contents

See the Create a new HelpNDoc project step-by-step guide.