Topics are managed as a tree-structure from the table of contents. A topic can contain any number of children topics which itself can contain any number of children topics and so on. Also topics are not sorted in any way in the table of contents so they can freely be positioned. To move a topic in the table of contents:

Note: The project topic can't be move. It is always the root of all the topics available in the project.

See the How to move topics in HelpNDoc step-by-step guide.